Downstream Process Of Amorphous Solid Dispersion

Synopsis

Solid dispersion is still one of the hot topics in the pharmaceutical industry. This presentation takes us to another lever were we discuss the down streaming process example which many formulators face issues especially when you use cellulose derivatives. We look at the options of using HPMCAS in hot melt extrusion and how you can overcome an issues you face when milling the extrudates or producing pellets. Another issues that formulators face is scaling up of spray dried material and how that has an impact on the release profile.