Tablet Defects: Can They Be Predicted?
Time: 2:50 pm - 3:00 pm
Date: 29 April 2020
Common tablet defects include chipping, picking & sticking, cracking, lamination & capping to name a few. Lamination & capping often occur during scale-up and are main issues in our industry. It is a common hurdle in tableting which is not generally observed during the R&D development phase. One of the reasons lie in the high production speeds on industrial rotary presses, speeds that are not generally seen on conventional R&D tablet presses. This explains why capping or lamination is sometimes only discovered during scale-up. It is essential to try to identify those issues at the very early stage of development.
- Bruno Leclerq Senior Pharmacist - Medelpharm