Screening of Pharmaceutical Polymorphs
Time: 9:15 am - 9:35 am
Date: 26 April 2023
Polymorph expert Ruwanthi Gurusinghe will talk Custom Pharma Services’ approach to the screening of Pharamceutical Polymorphs. More than 50% of commercially available drug candidates have more than one polymorphic form. Each morph may show differences in their physicochemical properties such as dissolution rate, bioavailability, physical and chemical stability. Various mechanical and environmental factors may cause… Read more »
Making PharmaceuticalsSynopsis
Polymorph expert Ruwanthi Gurusinghe will talk Custom Pharma Services’ approach to the screening of Pharamceutical Polymorphs.
More than 50% of commercially available drug candidates have more than one polymorphic form. Each morph may show differences in their physicochemical properties such as dissolution rate, bioavailability, physical and chemical stability. Various mechanical and environmental factors may cause unintentional transformations between different polymorphs. The presentation will cover:
An overview to the polymorphism.
- Factors which affect polymorphic transformations.
- The impact of polymorphic transformations in pharmaceutical compounds.
- The importance of identifying the ideal polymorphic phases of drug compounds.
- Polymorph screening techniques including X-ray crystallography, thermal methods, spectroscopic and microscopic.
Speakers
Dr Ruwanthi Gurusinghe Formulation Scientist - Custom Pharma Services
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