Long-acting Therapeutics Enabled by Nanomedicines

Synopsis

This presentation will explore the development of long-acting drug delivery systems designed to improve patient adherence in the treatment of chronic diseases. The focus will be on the design of injectable, in situ forming implants based on dual-stimuli responsive nanogels and solid drug nanoparticles. These nanocomposite drug depots enable controlled, long-term release by responding to body temperature and physiological conditions upon injection. The talk will cover the underlying polymer chemistry, formulation challenges, and pre-clinical evaluation of these systems, which hold the potential to enhance therapeutic outcomes by addressing poor adherence in chronic disease treatments