Continuous and Scalable Formulation of APIs

Synopsis

This presentation will describe how Promethean have developed a novel flow technology that can synthesise new materials (both organic and inorganic) to controlled specifications and the road from bench to industrial scale. The technology has also been used to formulate poorly soluble drugs to create nanocrystalline dispersions inside materials such as PVP at a range of scales from prototype (g’s) to pilot scale (kg’s) with the potential for mass manufacture. Work will also be presented in the creation of materials with novel porous structures that could be used in controlled drug release e.g. LDH’s and MOF’s.